This Virginian crossover band was formed in 1990 as Burn The Priest, but it was only when it did a complete u-turn name-wise that it was met with some success. Lamb Of God is a euphemism for Jesus. The band issued a demo and signed with Prosthetic Records. Its debut album, New American Gospel, was out in 2000 and established the band as a left-leaning new force in metal and hardcore. The album was supported through a video for the song Black Label.

As The Palaces Burn was produced by Devin Townsend at Montana Studio and featured an appearance by former Megadeth guitarist Chris Poland. The band gained a major label contract when it signed to Epic Records in the USA. A DVD called Terror And Hubris was issued at this time. Ashes Of The Wake had the band touring with Children Of Bodom. The album featured Chris Poland and landed in the Billboard charts. The group toured as part of Ozzfest in 2004. Adler was in and out of Machinations Of Dementia in 2005, a band, which also featured Cannibal Corpse’s Alex Webster. The group toured as part of Gigantour in 2006. Sacrament landed in the Billboard Top 10.

The group signed with Roadrunner Records in 2008 and was to issue a DVD in July. The thrashers picked Wrath as the title for the 2009 album. The record was issued in February by Epic in America and Roadrunner in Europe. Guitarist Mark Morton was not with the band during the last six shows of the band’s European tour in the summer of 2009 as his wife was expecting a baby. Unearth’s Buz McGrath would fill in for the shows. Lamb Of God played its first show in China on Sunday, April 11th, 2010 at Star Live in Beijing. A planned Shanghai show was never licensed. Lamb Of God singer Randy Blythe was held in Prague, Czech Republic after pushing a fan back from the stage more than two years ago. Daniel N. had jumped the stage, reportedly, for a third time. Blythe’s bail was set at $200,000. A Prague Municipal Court dismissed the Prague State Attorney's Office complaint against Lamb Of God singer Randy Blythe's release on bail. However, the court increased Blythe's bail from $200,000, which had already been deposited, to $400,000, reportedly equivalent to twice Randy's annual income. After return shows with singer Randy Blythe at Knotfest in August Lamb Of God has announced an autumn tour starting October 30th in Phoenix, Arizona with In Flames, Hellyeah and Sylosis opening at various stages.